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Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes

BACKGROUND: Lysosomes are acidic organelles that play multiple roles in various cellular oxidative activities such as the oxidative burst during cytotoxic killing. It remains to be determined how lysosomal lumen oxidative activity and pH interact and are regulated. Here, I report the use of fluoresc...

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Autore principale: Chen, Chii-Shiarng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC119861/
https://ncbi.nlm.nih.gov/pubmed/12165102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-3-21
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