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The isolation of neurophysin-I and -II from bovine pituitary neurosecretory granules separated on a large scale from other subcellular organelles. Demonstration of slow equilibration of neurosecretory granules during centrifugation in a sucrose density gradient

1. An improved procedure for the isolation of neurosecretory granules from the posterior lobe of the bovine pituitary gland is described. 2. Of the total oxytocic and pressor activities present in the original tissue 80% was sedimentable. 3. The granules were separated from mitochondria by prolonged...

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Bibliografiske detaljer
Main Authors: Dean, C. R., Hope, D. B.
Format: Artigo
Sprog:Inglês
Udgivet: 1968
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198538/
https://ncbi.nlm.nih.gov/pubmed/5637360
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