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Studies on the pathogenesis of liver necrosis by α-amanitin. Effect of α-amanitin on ribonucleic acid synthesis and on ribonucleic acid polymerase in mouse liver nuclei

1. Injection of α-amanitin to mice causes a decreased incorporation of [6-(14)C]-orotic acid into liver RNA in vivo. 2. The activity of RNA polymerase activated by Mn(2+) and ammonium sulphate is greatly impaired in liver nuclei isolated from mice poisoned with α-amanitin, and is inhibited by the ad...

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Hlavní autoři: Stirpe, F., Fiume, L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1967
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198379/
https://ncbi.nlm.nih.gov/pubmed/5584017
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