Identification of HLA-DRPheβ47 as the susceptibility marker of hypersensitivity to beryllium in individuals lacking the berylliosis-associated supratypic marker HLA-DPGluβ69

BACKGROUND: Susceptibility to beryllium (Be)-hypersensitivity (BH) has been associated with HLA-DP alleles carrying a glutamate at position 69 of the HLA-DP β-chain (HLA-DPGlu69) and with several HLA-DP, -DQ and -DR alleles and polymorphisms. However, no genetic associations have been found between...

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Detalhes bibliográficos
Main Authors: Amicosante, Massimo, Berretta, Floriana, Rossman, Milton, Butler, Richard H, Rogliani, Paola, van den Berg-Loonen, Ella, Saltini, Cesare
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198259/
https://ncbi.nlm.nih.gov/pubmed/16098233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-94
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