Up-Regulation and Profibrotic Role of Osteopontin in Human Idiopathic Pulmonary Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and excessive accumulation of extracellular matrix in the lung. METHODS AND FINDINGS: Using oligonucleotide arrays, we identified osteopontin as one of the genes that significantl...

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Detalhes bibliográficos
Main Authors: Pardo, Annie, Gibson, Kevin, Cisneros, José, Richards, Thomas J, Yang, Yinke, Becerril, Carina, Yousem, Samueal, Herrera, Iliana, Ruiz, Victor, Selman, Moisés, Kaminski, Naftali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198037/
https://ncbi.nlm.nih.gov/pubmed/16128620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020251
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