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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

Perturbations of the p53 pathway are associated with more aggressive and therapeutically refractory tumors. However, molecular assessment of p53 status, by using sequence analysis and immunohistochemistry, are incomplete assessors of p53 functional effects. We posited that the transcriptional finger...

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Detalhes bibliográficos
Main Authors: Miller, Lance D., Smeds, Johanna, George, Joshy, Vega, Vinsensius B., Vergara, Liza, Ploner, Alexander, Pawitan, Yudi, Hall, Per, Klaar, Sigrid, Liu, Edison T., Bergh, Jonas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1197273/
https://ncbi.nlm.nih.gov/pubmed/16141321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506230102
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