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A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

The ataxia telangiectasia mutant (ATM) protein kinase regulates the cell's response to DNA damage through the phosphorylation of proteins involved in cell-cycle checkpoints and DNA repair. However, the signal-transduction pathway linking DNA strand breaks to activation of ATM's kinase acti...

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Bibliographic Details
Main Authors: Sun, Yingli, Jiang, Xiaofeng, Chen, Shujuan, Fernandes, Norvin, Price, Brendan D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1197271/
https://ncbi.nlm.nih.gov/pubmed/16141325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504211102
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