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Single-Gene Disorders: What Role Could Moonlighting Enzymes Play?

Single-gene disorders with “simple” Mendelian inheritance do not always imply that there will be an easy prediction of the phenotype from the genotype, which has been shown for a number of metabolic disorders. We propose that moonlighting enzymes (i.e., metabolic enzymes with additional functional a...

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Hlavní autoři: Sriram, Ganesh, Martinez, Julian A., McCabe, Edward R. B., Liao, James C., Dipple, Katrina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196451/
https://ncbi.nlm.nih.gov/pubmed/15877277
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