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Strong Evidence of Linkage Disequilibrium between Polymorphisms at the IRF6 Locus and Nonsyndromic Cleft Lip With or Without Cleft Palate, in an Italian Population

Cleft lip with or without cleft palate (CL/P) is one of the most common birth defects, but its etiology is largely unknown. It is very likely that both genetic and environmental factors contribute to this malformation. Mutations in the gene for interferon regulatory factor 6 (IRF6) have been shown t...

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Bibliographic Details
Main Authors: Scapoli, Luca, Palmieri, Annalisa, Martinelli, Marcella, Pezzetti, Furio, Carinci, Paolo, Tognon, Mauro, Carinci, Francesco
Format: Artigo
Language:Inglês
Published: The American Society of Human Genetics 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196422/
https://ncbi.nlm.nih.gov/pubmed/15558496
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