Hypermutation Is a Key Factor in Development of Multiple-Antimicrobial Resistance in Pseudomonas aeruginosa Strains Causing Chronic Lung Infections

Pseudomonas aeruginosa is the most relevant pathogen producing chronic lung infections in patients with chronic underlying diseases such as cystic fibrosis (CF), bronchiectasis, and chronic obstructive pulmonary disease (COPD). Hypermutable (or mutator) P. aeruginosa strains, characterized by increa...

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Detalhes bibliográficos
Main Authors: Maciá, María D., Blanquer, David, Togores, Bernat, Sauleda, Jaume, Pérez, José L., Oliver, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196247/
https://ncbi.nlm.nih.gov/pubmed/16048951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3382-3386.2005
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