In Vitro and In Vivo Antibacterial Activities of CS-023 (RO4908463), a Novel Parenteral Carbapenem

CS-023 (RO4908463, formerly R-115685) is a novel 1β-methylcarbapenem with 5-substituted pyrrolidin-3-ylthio groups, including an amidine moiety at the C-2 position. Its antibacterial activity was tested against 1,214 clinical isolates of 32 species and was compared with those of imipenem, meropenem,...

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Detalhes bibliográficos
Main Authors: Koga, Tetsufumi, Abe, Tomomi, Inoue, Harumi, Takenouchi, Takashi, Kitayama, Akiko, Yoshida, Tatsuhiko, Masuda, Nobuhisa, Sugihara, Chika, Kakuta, Masayo, Nakagawa, Miyuki, Shibayama, Takahiro, Matsushita, Yoko, Hirota, Takashi, Ohya, Satoshi, Utsui, Yukio, Fukuoka, Takashi, Kuwahara, Syogo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196225/
https://ncbi.nlm.nih.gov/pubmed/16048932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3239-3250.2005
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