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The Lipopolysaccharide of Brucella abortus BvrS/BvrR Mutants Contains Lipid A Modifications and Has Higher Affinity for Bactericidal Cationic Peptides

The two-component BvrS/BvrR system is essential for Brucella abortus virulence. It was shown previously that its dysfunction abrogates expression of some major outer membrane proteins and increases bactericidal peptide sensitivity. Here, we report that BvrS/BvrR mutants have increased surface hydrop...

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Bibliographic Details
Main Authors: Manterola, Lorea, Moriyón, Ignacio, Moreno, Edgardo, Sola-Landa, Alberto, Weiss, David S., Koch, Michel H. J., Howe, Jörg, Brandenburg, Klaus, López-Goñi, Ignacio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196083/
https://ncbi.nlm.nih.gov/pubmed/16077108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.16.5631-5639.2005
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