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Amino Acids in Positions 48, 52, and 73 Differentiate the Substrate Specificities of the Highly Homologous Chlorocatechol 1,2-Dioxygenases CbnA and TcbC

Chlorocatechol 1,2-dioxygenase (CCD) is the first-step enzyme of the chlorocatechol ortho-cleavage pathway, which plays a central role in the degradation of various chloroaromatic compounds. Two CCDs, CbnA from the 3-chlorobenzoate-degrader Ralstonia eutropha NH9 and TcbC from the 1,2,4-trichloroben...

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Autors principals: Liu, Shenghao, Ogawa, Naoto, Senda, Toshiya, Hasebe, Akira, Miyashita, Kiyotaka
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196051/
https://ncbi.nlm.nih.gov/pubmed/16030237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.15.5427-5436.2005
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