Effects of Intratracheal Administration of Novispirin G10 on a Rat Model of Mucoid Pseudomonas aeruginosa Lung Infection

Chronic Pseudomonas aeruginosa lung infection is a major problem for patients with cystic fibrosis (CF). The biofilm mode of growth of the pathogen makes it highly resistant to antibiotic treatment, and this is especially pronounced with mucoid strains. In this study, novispirin G10, a synthetic ant...

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Bibliographic Details
Main Authors: Song, Zhijun, Wu, Hong, Mygind, Per, Raventos, Dora, Sonksen, Carsten, Kristensen, Hans-Henrik, Høiby, Niels
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195441/
https://ncbi.nlm.nih.gov/pubmed/16127064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3868-3874.2005
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