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Effect of Simvastatin, an Established Lipid-Lowering Drug, on Pulmonary Chlamydia pneumoniae Infection in Mice

The effects of simvastatin treatment on Chlamydia pneumoniae lung infection, inflammation, and serum lipids in mouse model were studied. Simvastatin decreased viable chlamydial counts and increased inflammatory cell infiltrates in the lung tissue, suggesting that simvastatin treatment had both antic...

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Autors principals: Erkkilä, Leena, Jauhiainen, Matti, Laitinen, Kirsi, Haasio, Kristiina, Tiirola, Terttu, Saikku, Pekka, Leinonen, Maija
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195438/
https://ncbi.nlm.nih.gov/pubmed/16127082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3959-3962.2005
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