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Renouncing electroneutrality is not free of charge: Switching on electrogenicity in a Na(+)-coupled phosphate cotransporter

Renal type IIa Na(+)-coupled inorganic phosphate (P(i)) cotransporters (NaPi-IIa) mediate divalent P(i) transport in an electrogenic manner, whereas the renal type IIc isoform (NaPi-IIc) is electroneutral, yet it shows high sequence identity with NaPi-IIa. Dual uptake ((32)P(i)/(22)Na) assays confir...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bacconi, Andrea, Virkki, Leila V., Biber, Jürg, Murer, Heini, Forster, Ian C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194947/
https://ncbi.nlm.nih.gov/pubmed/16113079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505882102
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