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Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT(3) receptors

The 5-HT(3) receptor is a cation-selective ligand-gated ion channel of the Cys-loop superfamily. The receptor is an important therapeutic target, with receptor antagonists being widely used as antiemetics in cancer therapy. The two known receptor subunits, A and B, form homomeric 5-HT(3A) receptors...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barrera, Nelson P., Herbert, Paul, Henderson, Robert M., Martin, Ian L., Edwardson, J. Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194916/
https://ncbi.nlm.nih.gov/pubmed/16116092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503253102
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