Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid

Group B streptococci (GBSs) are the leading cause of neonatal meningitis. GBSs enter the CNS by penetrating the blood-brain barrier (BBB), which consists of specialized human brain microvascular endothelial cells (hBMECs). To identify GBS factors required for BBB penetration, we generated random mut...

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Detalhes bibliográficos
Main Authors: Doran, Kelly S., Engelson, Erin J., Khosravi, Arya, Maisey, Heather C., Fedtke, Iris, Equils, Ozlem, Michelsen, Kathrin S., Arditi, Moshe, Peschel, Andreas, Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193870/
https://ncbi.nlm.nih.gov/pubmed/16138192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23829
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