A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

The receptor binding specificity of influenza viruses may be important for host restriction of human and avian viruses. Here, we show that the hemagglutinin (HA) of the virus that caused the 1918 influenza pandemic has strain-specific differences in its receptor binding specificity. The A/South Caro...

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Hlavní autoři: Glaser, Laurel, Stevens, James, Zamarin, Dmitriy, Wilson, Ian A., García-Sastre, Adolfo, Tumpey, Terrence M., Basler, Christopher F., Taubenberger, Jeffery K., Palese, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193621/
https://ncbi.nlm.nih.gov/pubmed/16103207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11533-11536.2005
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