A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

The receptor binding specificity of influenza viruses may be important for host restriction of human and avian viruses. Here, we show that the hemagglutinin (HA) of the virus that caused the 1918 influenza pandemic has strain-specific differences in its receptor binding specificity. The A/South Caro...

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Détails bibliographiques
Auteurs principaux: Glaser, Laurel, Stevens, James, Zamarin, Dmitriy, Wilson, Ian A., García-Sastre, Adolfo, Tumpey, Terrence M., Basler, Christopher F., Taubenberger, Jeffery K., Palese, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193621/
https://ncbi.nlm.nih.gov/pubmed/16103207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11533-11536.2005
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