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Cisplatin Nephrotoxicity and Protection by Milk Thistle Extract in Rats

The protective effect of methanolic extract of milk thistle seeds and silymarin against cisplatin-induced renal toxicity in male rats after a single intraperitoneal injection of 3 mg kg(−1) cisplatin were studied. Over 5 days, cisplatin-treated rats showed tubular necrosis and elevation in blood ure...

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Detalhes bibliográficos
Main Authors: Karimi, Gholamreza, Ramezani, Mohammad, Tahoonian, Zahra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193544/
https://ncbi.nlm.nih.gov/pubmed/16136217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecam/neh103
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