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Trifluoperazine reduces inward ionic currents and secretion by separate mechanisms in bovine chromaffin cells.

Using patch-clamp techniques, excitation and secretion in chromaffin cells were studied by measurement of unitary inward currents and of stimulus-evoked increments in membrane capacitance. The effect of the calmodulin inhibitor trifluoperazine (TFP) on Na, Ca and acetylcholine-induced (ACh) currents...

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Détails bibliographiques
Auteurs principaux: Clapham, D E, Neher, E
Format: Artigo
Langue:Inglês
Publié: 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193321/
https://ncbi.nlm.nih.gov/pubmed/6090644
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