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Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors
BACKGROUND: The cell-membrane G-protein coupled receptors (GPCRs) are one of the largest known superfamilies and are the main focus of intense pharmaceutical research due to their key role in cell physiology and disease. A large number of putative GPCRs are 'orphans' with no identified nat...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1192796/ https://ncbi.nlm.nih.gov/pubmed/16091152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-106 |
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