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Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors

BACKGROUND: The cell-membrane G-protein coupled receptors (GPCRs) are one of the largest known superfamilies and are the main focus of intense pharmaceutical research due to their key role in cell physiology and disease. A large number of putative GPCRs are 'orphans' with no identified nat...

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Detalhes bibliográficos
Main Authors: Metpally, Raghu Prasad Rao, Sowdhamini, Ramanathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1192796/
https://ncbi.nlm.nih.gov/pubmed/16091152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-106
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