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Free-calcium and force transients during depolarization and pharmacomechanical coupling in guinea-pig smooth muscle.

1. Fura2 was loaded by permeation and hydrolysis of the acetoxymethyl ester into smooth muscle cells of intact thin sheets of the longitudinal layer of the small intestine of the guinea-pig, to record Ca2+ transients during contraction. 2. Cytoplasmic Ca2+ ([Ca2+]i) was monitored by computing the ra...

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Detalhes bibliográficos
Main Authors: Himpens, B, Somlyo, A P
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1192007/
https://ncbi.nlm.nih.gov/pubmed/3137325
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