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Effect of glutamine on methotrexate efficacy and toxicity.

OBJECTIVE: To examine the effect of oral glutamine (GLN) on the efficacy and toxicity of methotrexate (MTX). SUMMARY BACKGROUND DATA: The use of high-dose chemotherapy regimens is limited by the severity of their toxicities. Oral GLN has been shown to decrease the gut toxicity seen with MTX treatmen...

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Detalhes bibliográficos
Main Authors: Rubio, I T, Cao, Y, Hutchins, L F, Westbrook, K C, Klimberg, V S
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1191365/
https://ncbi.nlm.nih.gov/pubmed/9605669
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