Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures.

1. Employing a primary cell culture system and intracellular microelectrodes, we quantitated and compared the Na+ and Cl- pathways in apical membranes of normal and cystic fibrosis (CF) human airway epithelia. 2. Like the transepithelial difference (PD) in situ, the PD of CF epithelia in culture (-2...

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Hauptverfasser: Boucher, R C, Cotton, C U, Gatzy, J T, Knowles, M R, Yankaskas, J R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190965/
https://ncbi.nlm.nih.gov/pubmed/3255805
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