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Pertussis toxin inhibits endothelium-dependent relaxations to certain agonists in porcine coronary arteries.

1. Pertussis toxin inactivates Gi-protein, which mediates the inhibitory effects of receptors on adenylate cyclase. The effects of the toxin on endothelium-dependent and independent relaxations were determined in porcine coronary arteries. 2. Arterial rings (with and without endothelium) were suspen...

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Main Authors: Flavahan, N A, Shimokawa, H, Vanhoutte, P M
格式: Artigo
語言:Inglês
出版: 1989
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190419/
https://ncbi.nlm.nih.gov/pubmed/2778738
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