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Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-γ

Genetic defects in the IFN-γ response pathway cause unique susceptibility to intracellular pathogens, particularly mycobacteria, but are rare and do not explain mycobacterial disease in the majority of affected patients. We postulated that acquired defects in macrophage activation by IFN-γ may cause...

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Detalhes bibliográficos
Main Authors: Kampmann, Beate, Hemingway, Cheryl, Stephens, Alick, Davidson, Robert, Goodsall, Anna, Anderson, Suzanne, Nicol, Mark, Schölvinck, Elisabeth, Relman, David, Waddell, Simon, Langford, Paul, Sheehan, Brian, Semple, Lynn, Wilkinson, Katalin A., Wilkinson, Robert J., Ress, Stanley, Hibberd, Martin, Levin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190367/
https://ncbi.nlm.nih.gov/pubmed/16127458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI19316
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