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Transformation of Human and Murine Fibroblasts without Viral Oncoproteins

Murine embryo fibroblasts are readily transformed by the introduction of specific combinations of oncogenes; however, the expression of those same oncogenes in human cells fails to convert such cells to tumorigenicity. Using normal human and murine embryonic fibroblasts, we show that the transformat...

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Autors principals: Boehm, Jesse S., Hession, Meghan T., Bulmer, Sara E., Hahn, William C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190359/
https://ncbi.nlm.nih.gov/pubmed/16024784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6464-6474.2005
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