Mice Lacking the UBC4-testis Gene Have a Delay in Postnatal Testis Development but Normal Spermatogenesis and Fertility

Activation of ubiquitination occurs during spermatogenesis and is dependent on the induction of isoforms of the UBC4 family of ubiquitin-conjugating enzymes. The UBC4-testis isoform is testis specific, is induced in round spermatids, and demonstrates biochemical functions distinct from a ubiquitousl...

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Autors principals: Bedard, Nathalie, Hingamp, Pascal, Pang, Zhiyu, Karaplis, Andrew, Morales, Carlos, Trasler, Jacquetta, Cyr, Dan, Gagnon, Claude, Wing, Simon S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190331/
https://ncbi.nlm.nih.gov/pubmed/16024774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6346-6354.2005
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