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Role of the Mammalian RNA Polymerase II C-Terminal Domain (CTD) Nonconsensus Repeats in CTD Stability and Cell Proliferation

The C-terminal domain (CTD) of mammalian RNA polymerase II (Pol II) consists of 52 repeats of the consensus heptapeptide YSPTSPS and links transcription to the processing of pre-mRNA. The length of the CTD and the number of repeats diverging from the consensus sequence have increased through evoluti...

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Autori principali: Chapman, Rob D., Conrad, Marcus, Eick, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190292/
https://ncbi.nlm.nih.gov/pubmed/16107713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7665-7674.2005
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