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ELAV Multimerizes on Conserved AU(4-6) Motifs Important for ewg Splicing Regulation

ELAV is a gene-specific regulator of alternative pre-mRNA processing in Drosophila neurons. Since ELAV/Hu proteins preferentially bind to AU-rich regions that are generally abundant in introns and untranslated regions, it has not been clear how gene specificity is achieved. Here we used a combinatio...

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Détails bibliographiques
Auteurs principaux: Soller, Matthias, White, Kalpana
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190278/
https://ncbi.nlm.nih.gov/pubmed/16107705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7580-7591.2005
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