Defining the Domains of Human Polynucleotide Phosphorylase (hPNPase(OLD-35)) Mediating Cellular Senescence

To fully comprehend cellular senescence, identification of relevant genes involved in this process is mandatory. Human polynucleotide phosphorylase (hPNPase(OLD-35)), an evolutionarily conserved 3′, 5′ exoribonuclease mediating mRNA degradation, was first identified as a predominantly mitochondrial...

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Detalles Bibliográficos
Autores principales: Sarkar, Devanand, Park, Eun Sook, Emdad, Luni, Randolph, Aaron, Valerie, Kristoffer, Fisher, Paul B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190265/
https://ncbi.nlm.nih.gov/pubmed/16055741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7333-7343.2005
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