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HIP-55 Is Important for T-Cell Proliferation, Cytokine Production, and Immune Responses

Engagement of the T-cell receptor (TCR) triggers a series of signaling events that lead to the activation of T cells. HIP-55 (SH3P7 or mAbp1), an actin-binding adaptor protein, interacts with and is tyrosine phosphorylated by ZAP-70, which is a crucial proximal protein tyrosine kinase for TCR signal...

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Autori principali: Han, Jin, Shui, Jr-Wen, Zhang, Xuejun, Zheng, Biao, Han, Shuhua, Tan, Tse-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190228/
https://ncbi.nlm.nih.gov/pubmed/16055701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6869-6878.2005
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