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Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke

BACKGROUND: While gelatinase (MMP-2 and -9) activity is increased after focal ischemia/reperfusion injury in the brain, the relative contribution of neutrophils to the MMP activity and to the development of hemorrhagic transformation remains unknown. RESULTS: Anti-PMN treatment caused successful dep...

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Autors principals: Harris, Alex K, Ergul, Adviye, Kozak, Anna, Machado, Livia S, Johnson, Maribeth H, Fagan, Susan C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190186/
https://ncbi.nlm.nih.gov/pubmed/16078993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-6-49
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