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Decreased sensitivity of contraction to changes of intracellular pH in papillary muscle from diabetic rat hearts.

1. The relationship between intracellular pH (pHi) and contractile activity was investigated in papillary muscles isolated from right ventricle of normal and streptozotocin (STZ)-induced diabetic rats. pHi changes induced by 20 mM-NH4Cl were recorded with H(+)-sensitive microelectrodes. 2. An increa...

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Bibliographic Details
Main Authors: Lagadic-Gossmann, D, Feuvray, D
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190144/
https://ncbi.nlm.nih.gov/pubmed/2352189
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