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Toward a live microbial microbicide for HIV: Commensal bacteria secreting an HIV fusion inhibitor peptide

Most HIV transmission occurs on the mucosal surfaces of the gastrointestinal and cervicovaginal tracts, both of which are normally coated by a biofilm of nonpathogenic commensal bacteria. We propose to genetically engineer such naturally occurring bacteria to protect against HIV infection by secreti...

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Detalhes bibliográficos
Main Authors: Rao, Srinivas, Hu, Stella, McHugh, Louise, Lueders, Kira, Henry, Ken, Zhao, Qi, Fekete, Richard A., Kar, Sudeshna, Adhya, Sankar, Hamer, Dean H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189328/
https://ncbi.nlm.nih.gov/pubmed/16040799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504881102
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