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Neuronal ELAV proteins enhance mRNA stability by a PKCα-dependent pathway

More than 1 in 20 human genes bear in the mRNA 3′ UTR a specific motif called the adenine- and uridine-rich element (ARE), which posttranscriptionally determines its expression in response to cell environmental signals. ELAV (embryonic lethal abnormal vision) proteins are the only known ARE-binding...

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Detalhes bibliográficos
Main Authors: Pascale, Alessia, Amadio, Marialaura, Scapagnini, Giovanni, Lanni, Cristina, Racchi, Marco, Provenzani, Alessandro, Govoni, Stefano, Alkon, Daniel L., Quattrone, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189326/
https://ncbi.nlm.nih.gov/pubmed/16099831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504702102
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