Caricamento...

Unraveling a role for dopamine in Huntington's disease: The dual role of reactive oxygen species and D2 receptor stimulation

Huntington's disease (HD), an inherited neurodegenerative disorder, results from an abnormal polyglutamine extension in the N-terminal region of the huntingtin protein. This mutation leads to protein aggregation and neurotoxicity. Despite its widespread expression in the brain and body, mutated...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Charvin, Delphine, Vanhoutte, Peter, Pagès, Christiane, Borelli, Emiliana, Caboche, Jocelyne
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189314/
https://ncbi.nlm.nih.gov/pubmed/16103364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502698102
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !