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Activation and desensitization mechanisms of muscarinic current response in single pancreatic acinar cells of rats.

1. In single, enzymatically dissociated, rat pancreatic acinar cells both ACh stimulation and IP3 (inositol 1,4,5-trisphosphate) injection can evoke Ca(+)-dependent transient current responses. However, exogenously applied IP3 (10 microM) gradually loses its ability to induce the Ca2(+)-dependent re...

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Autor principal: Maruyama, Y
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189270/
https://ncbi.nlm.nih.gov/pubmed/2621598
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