Fibroblast growth factors share binding sites in heparan sulphate

HS (heparan sulphate) proteoglycans bind secreted signalling proteins, including FGFs (fibroblast growth factors) through their HS side chains. Such chains contain a wealth of differentially sulphated saccharide epitopes. Whereas specific HS structures are commonly believed to modulate FGF-binding a...

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Bibliografiske detaljer
Main Authors: Kreuger, Johan, Jemth, Per, Sanders-Lindberg, Emil, Eliahu, Liat, Ron, Dina, Basilico, Claudio, Salmivirta, Markku, Lindahl, Ulf
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1188264/
https://ncbi.nlm.nih.gov/pubmed/15769253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20042129
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