Tonsillar homing of Epstein-Barr virus–specific CD8+ T cells and the virus-host balance

Patients with infectious mononucleosis (IM) undergoing primary EBV infection show large expansions of EBV-specific CD8(+) T cells in the blood. While latent infection of the B cell pool is quickly controlled, virus shedding from lytically infected cells in the oropharynx remains high for several mon...

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Main Authors: Hislop, Andrew D., Kuo, Michael, Drake-Lee, Adrian B., Akbar, Arne N., Bergler, Wolfgang, Hammerschmitt, Nicolas, Khan, Naeem, Palendira, Umaimainthan, Leese, Alison M., Timms, Judith M., Bell, Andrew I., Buckley, Christopher D., Rickinson, Alan B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187932/
https://ncbi.nlm.nih.gov/pubmed/16110323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24810
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