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Evidence of a Double-Lid Movement in Pseudomonas aeruginosa Lipase: Insights from Molecular Dynamics Simulations

Pseudomonas aeruginosa lipase is a 29-kDa protein that, following the determination of its crystal structure, was postulated to have a lid that stretched between residues 125 and 148. In this paper, using molecular dynamics simulations, we propose that there exists, in addition to the above-mentione...

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Main Authors: Cherukuvada, Subbulakshmi Latha, Seshasayee, Aswin Sai Narain, Raghunathan, Krishnan, Anishetty, Sharmila, Pennathur, Gautam
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187864/
https://ncbi.nlm.nih.gov/pubmed/16110344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0010028
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