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Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal
The structure of human telomere DNA is of intense interest because of its role in the biology of both cancer and aging. The sequence [5′-AGGG(TTAGGG)(3)] has been used as a model for telomere DNA in both NMR and X-ray crystallographic studies, the results of which show dramatically different structu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1187823/ https://ncbi.nlm.nih.gov/pubmed/16106044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki782 |
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