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DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE
POU domain proteins contain a bipartite DNA-binding element that can confer allosteric control of coactivator recruitment. Dimerization of Oct-1 and Oct-2 on palindromic response elements results in the conformational dependent inclusion or exclusion of the transcriptional coactivator OBF-1. In this...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1187819/ https://ncbi.nlm.nih.gov/pubmed/16103132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki744 |
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