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Conditions for the self-catalysed inactivation of carnitine acetyltransferase. A novel form of enzyme inhibition

1. Carnitine acetyltransferase is very rapidly inhibited in the presence of bromoacetyl-(−)-carnitine plus CoA or of bromoacetyl-CoA plus (−)-carnitine. 2. Under appropriate conditions, the enzyme may be titrated with either bromoacetyl substrate analogue; in each case about 1mole of inhibitor is re...

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Detalhes bibliográficos
Main Authors: Chase, J. F. A., Tubbs, P. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 1969
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187810/
https://ncbi.nlm.nih.gov/pubmed/5763788
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