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The mechanisms of reductive carboxylation reactions. Carbon dioxide or bicarbonate as substrate of nicotinamide-adenine dinucleotide phosphate-linked isocitrate dehydrogenase and `malic' enzyme

1. A simple kinetic method was devised to show whether dissolved CO(2) or HCO(3)– ion is the substrate in enzyme-catalysed carboxylation reactions. 2. The time-course of the reductive carboxylation of 2-oxoglutarate by NADPH, catalysed by isocitrate dehydrogenase, was studied by a sensitive fluorime...

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Detalhes bibliográficos
Main Authors: Dalziel, K., Londesborough, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187201/
https://ncbi.nlm.nih.gov/pubmed/4387225
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