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Calprotectin inhibits matrix metalloproteinases by sequestration of zinc

Background/Aims—Calprotectin, a 36 kDa protein present in neutrophil cytoplasm, has antimicrobial and apoptosis inducing activities, which are reversed by the addition of zinc. Matrix metalloproteinases (MMPs), a family of zinc dependent enzymes, are important in many normal biological processes inc...

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Detalhes bibliográficos
Main Authors: Isaksen, B, Fagerhol, M K
Formato: Artigo
Idioma:Inglês
Publicado em: British Medical Journal Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187084/
https://ncbi.nlm.nih.gov/pubmed/11577169
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