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A unique junctional palindromic sequence in mitochondrial DNA from a patient with progressive external ophthalmoplegia
A polymerase chain reaction (PCR) based procedure was modified to determine the deletion of mitochondrial DNA (mtDNA). The protocol consists of coamplification both of deleted and wild-type segments of mtDNA using a long PCR technique; evaluation of the deleted portion within the amplified DNA segme...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
British Medical Journal Publishing Group
2000
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186989/ https://ncbi.nlm.nih.gov/pubmed/11193053 |
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