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The fate of 7[(14)C]-methylguanine after administration to the rat

1. To assess the significance of the methylation of nucleic acids known to be caused by certain carcinogens, the metabolic fate of 7[(14)C]-methylguanine was studied, with special reference to its possible incorporation into RNA and DNA. 2. The major part (approx. 95%) of the dose was excreted uncha...

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Detalhes bibliográficos
Main Authors: Craddock, Valda M., Mattocks, A. R., Magee, P. N.
Formato: Artigo
Idioma:Inglês
Publicado em: 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186754/
https://ncbi.nlm.nih.gov/pubmed/5669851
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