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Identification and characterization of a second 4,4′-dibenzamido-2,2′-stilbenedisulphonate (DBDS)-binding site on band 3 and its relationship with the anion/proton co-transport function

Band 3 mediates both electroneutral AE (anion exchange) and APCT (anion/proton co-transport). Protons activate APCT and inhibit AE with the same pK (∼5.0). SDs (stilbenedisulphonates) bind to a primary, high-affinity site on band 3 and inhibit both AE and APCT functions. In this study, we present fl...

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Bibliografiske detaljer
Main Authors: Salhany, James M., Cordes, Karen S., Sloan, Renee L.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186724/
https://ncbi.nlm.nih.gov/pubmed/15647006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041211
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